Title:
大環状ラクタムおよびその医薬的使用
Document Type and Number:
Japanese Patent JP4628366
Kind Code:
B2
Abstract:
The present invention relates to novel macrocyclic compounds of the formula wherein R1, R2, R3, U, V, W, X, Y, Z and n are as defined in the specification, the number of ring atoms included in the macrocyclic ring being 14, 15, 16 or 17, in free base form or in acid addition salt form, to their preparation, to their use as pharmaceuticals and to pharmaceutical compositions comprising them.
Inventors:
Eve oberson
Claudia Beccart
Ralph Glatthal
Kurt Raumen
Reiner Machuer
Marina Tintelknot-Bromlai
Thomas Yott Troxler
Seem Jacob Fernstra
Claudia Beccart
Ralph Glatthal
Kurt Raumen
Reiner Machuer
Marina Tintelknot-Bromlai
Thomas Yott Troxler
Seem Jacob Fernstra
Application Number:
JP2006538745A
Publication Date:
February 09, 2011
Filing Date:
November 04, 2004
Export Citation:
Assignee:
Novartis Age
International Classes:
C07D245/02; C07D255/00; C07D255/02; C07D273/00; C07D281/00; C07D285/00; C07D401/12; C07D471/08; C07D487/08; C07D498/08; C07D513/08; A61K31/395; A61K31/4353; A61K31/4427; A61P9/00; A61P25/00; A61P25/28; A61P35/00; A61P35/04; A61P43/00
Foreign References:
WO2002100856A1 | ||||
WO2002100399A1 |
Attorney, Agent or Firm:
Aoyama Aoi
Mitsutaka Iwasaki
Mitsutaka Iwasaki