Title:
MANUFACTURE OF ARALKYLAMINE
Document Type and Number:
Japanese Patent JPS54138528
Kind Code:
A
Abstract:
Aralkylamines of the formula: R1-CH2-N(R3)-R2 wherein R1 is a phenyl substituted by one of: (I) alkyls, (II) halo and (III) nitro; R2 is (IV) alkyl having from 4 to 10 carbon atoms, four of which are in one chain, (V) alkyl interrupted by an oxygen atom, i.e. an alkoxyalkyl or ether radical, or (VI) hydroxyalkyl wherein the alkyl is either (IV) or (V) and the hydroxy is the sole substituent; R3 is a hydrogen atom, alkyl having from 1 to 4 carbon atoms or such alkyl substituted by a dialkylphosphinyl group; a physiologically-compatible acid-addition salt thereof and a pharmaceutical composition containing such compound(s) as active ingredient(s) are valuable in view of the physiological activity, e.g. vasotonic, capillary sealing and antiarrhythmic, of the aralkylamines and their physiologically-compatible acid-addition salts.
Inventors:
FUORUKUHERU BORUMAN
RORUFU ORUTOUIN UEEBERU
ARUFUONSU ZEDERU
ISUTOBUAN BOKUZAI
RORUFU ORUTOUIN UEEBERU
ARUFUONSU ZEDERU
ISUTOBUAN BOKUZAI
Application Number:
JP12525378A
Publication Date:
October 27, 1979
Filing Date:
October 13, 1978
Export Citation:
Assignee:
HOECHST AG
International Classes:
A61K31/13; A61K31/135; A61K31/66; A61P9/00; A61P9/06; A61P9/08; C07C67/00; C07C209/00; C07C209/08; C07C209/26; C07C209/50; C07C211/27; C07C211/29; C07C213/00; C07C213/02; C07C215/08; C07C217/08; C07C301/00; C07C307/02; C07F9/32; C07F9/53; (IPC1-7): A61K31/135; A61K31/66; C07C85/08; C07C87/28; C07C93/02; C07F9/53
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