Title:
微粉砕粉末カロテノイド製剤の製造
Document Type and Number:
Japanese Patent JP4837812
Kind Code:
B2
Abstract:
The present invention relates to a continous process for the preparation of a pulverous carotenoid, retinoid or natural colourant preparation, wherein the active ingredient is finely divided, which process comprises the steps of a) forming a suspension of the active ingredient in a water-immiscible organic solvent optionally containing an antioxidant and/or an oil, b) feeding the suspension of step a) to a heat exchanger and heating said suspension to 100-250 DEG C, whereby the residence time in the heat exchanger is less than 5 see, c) rapidly mixing the solution of step b) at a temperature in the range of 20-100 DEG C with an aqueous solution of a swellable colloid optionally containing a stabilizer, d) removing the organic solvent and e) converting the dispersion of step d) into a pulverous preparation.
Inventors:
Hermann Stein
Klaus Viador
Bin Young
Klaus Viador
Bin Young
Application Number:
JP4259499A
Publication Date:
December 14, 2011
Filing Date:
February 22, 1999
Export Citation:
Assignee:
DSM IP ASSETS B.V.
International Classes:
C07C403/24; C09B61/00; A23L5/44; C09B67/04
Domestic Patent References:
| JP57195161A | ||||
| JP51041732A |
Attorney, Agent or Firm:
Yuichi Yamada
Masakazu Noda
Yoshinori Shimizu
Masakazu Noda
Yoshinori Shimizu