MANUFACTURE OF GUANIDINES AND INTERMEDIATES

Title:

MANUFACTURE OF GUANIDINES AND INTERMEDIATES

Document Type and Number:

Japanese Patent JPS61263957

Kind Code:

A

Abstract:

Novel synthetic steps and intermediates leading to guanidines such as the anti-diabetic compound linogliride. Included is a hydrogen peroxide oxidation of a thiourea (II) to a sulfonic acid (I) which may then be reacted with morpholine to form the carboximidamide (III):

Inventors:

SHINSHIA AN MAAYANOFU
JIEIMUZU NERUSON PURANPIN
ROBIN KOSUGUROOBU SUTANJION

Application Number:

JP5513786A

Publication Date:

November 21, 1986

Filing Date:

March 14, 1986

Export Citation:

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Assignee:

MCNEILAB INC

International Classes:

B01J23/00; C07B61/00; C07C67/00; C07C301/00; C07C303/16; C07D207/22; C07C309/16; C07C313/00; C07C335/16; C07C381/14; C07D207/273; C07D295/14; C07D295/215; C07D207/26; (IPC1-7): B01J23/28; C07C143/14; C07C149/42; C07D207/22; C07D295/14

Attorney, Agent or Firm:

Heikichi Odashima

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