Title:
MANUFACTURE OF QUINOLINE-3-CARBOXYLIC ACID ANTIBACTERIAL
Document Type and Number:
Japanese Patent JPS61238779
Kind Code:
A
Abstract:
An improved process for the preparation of 7-substituted amino-1-cyclopropyl-6,8-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids of formulais described where an alkyl ester of a 6,7,8-trifluoro precursor is converted to a trialkylsilyl ester which fluorine at C7 is directly displaced to the desired product.
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Inventors:
JIYON EMU DOOMAGARA
MERU SHII SHIYUREEDAA
MERU SHII SHIYUREEDAA
Application Number:
JP8440386A
Publication Date:
October 24, 1986
Filing Date:
April 14, 1986
Export Citation:
Assignee:
WARNER LAMBERT CO
International Classes:
A61K31/47; A61P31/04; C07D215/56; C07D401/04; C07D451/04; C07D471/08; C07D487/08; C07D487/10; C07F7/18; (IPC1-7): A61K31/47; C07D207/00; C07D215/00; C07D215/56; C07D221/00; C07D401/04; C07D471/08; C07D487/08
Attorney, Agent or Firm:
Chika Takagi
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