カルコブトロールの製造方法 - Engie Chem Life Sciences Corporation

Title:

カルコブトロールの製造方法

Document Type and Number:

Japanese Patent JP7071760

Kind Code:

B2

Abstract:

Disclosed is a method for producing calcobutrol used as an MRI contrast agent. The method comprises the steps of: obtaining butrol represented by chemical formula 2 in the specification by reacting a gadobutrol represented by chemical formula 1 in the specification and a decomplexing agent; and obtaining a calcobutrol represented by chemical Formula 3 in the specification by reacting butrol with calcium ions.

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Inventors:

Lee Jae Young
Lee Jong Soo
Byeong-kyu
Lee Byung Woo
Isano
Yun Tae Myung
Bang Jehun
Song Kiyoung

Application Number:

JP2020539828A

Publication Date:

May 19, 2022

Filing Date:

January 11, 2019

Export Citation:

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Assignee:

Engie Chem Life Sciences Corporation

International Classes:

C07D257/02

Domestic Patent References:

JP2013510117A

Foreign References:

CN106187930A
WO2017103258A1

Other References:

PLATZEK, J.,Inorg. Chem.,1997年,36,6086-6093

Attorney, Agent or Firm:

Kenjiro Yamaguchi
Kenichi Morita

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