Title:
α-ハロケトン、α-ハロヒドリン及びエポキシドの製造法
Document Type and Number:
Japanese Patent JP3665343
Kind Code:
B2
Abstract:
Processes for efficiently producing alpha -halo ketones, alpha -halohydrins and epoxides on an industrial scale. The prosesses include one for producing an alpha -halo ketone of general formula (3) by decarboxylating a product of reaction between a carboxilic acid derivative of general formula (1) and a metal enolate prepared from an alpha -haloacetic acid of general formula (2) or an acceptable salt thereof, one for producing an by reducing the alpha -halo ketone (3), and one for producing an epoxide (13) by treating the alpha -halohydrin (11) with a base to effect ring closure. The above prosesses are particularly suitable for producing optically active alpha -halo ketones, alpha -halohydrins and epoxides from the corresponding alpha -amino acid derivatives. R<1>COA
Inventors:
Akira Nishiyama
Tadashi Sugakawa
Hajime Manabe
Kenji Inoue
Noritaka Yoshida
Tadashi Sugakawa
Hajime Manabe
Kenji Inoue
Noritaka Yoshida
Application Number:
JP52342096A
Publication Date:
June 29, 2005
Filing Date:
February 02, 1996
Export Citation:
Assignee:
Kaneka Corporation
International Classes:
C07C29/143; C07C45/48; C07C269/06; C07C319/20; C07D303/36; C07C323/43; (IPC1-7): C07C45/48; C07C29/143; C07C33/46; C07C49/80; C07C211/00; C07C213/00; C07C215/28; C07C225/16; C07D301/26; C07D303/16; C07D303/36
Domestic Patent References:
| JP5286900A | ||||
| JP4244041A | ||||
| JP8225557A |
Foreign References:
| GB1233678A |
Attorney, Agent or Firm:
Yasuo Yasutomi
Shinya Furuya
Shinya Furuya