To manufacture a high purity hyaluronic acid and its salt by a simple method.
A manufacturing method of the high purity hyaluronic acid and its salt includes a purification step of performing an activated carbon adding operation for adding activated carbon into an aqueous liquid containing the hyaluronic acid and the like, a synthetic adsorbent adding operation for adding a (meth)acrylate based synthetic adsorbent and a filtering operation. In the purification step, activated carbon treatment by which a filtering operation is performed to the aqueous liquid containing the hyaluronic acid or its salt after the activated carbon adding operation and synthetic adsorbent treatment by which a filtering operation is performed to the filtrate obtained by the activated carbon treatment after the synthetic adsorbent adding operation are preferably performed in this order.
NINOMIYA HIROFUMI
SAWADA HIROAKI
TATSUNO KOICHIRO
JPS63270701A | 1988-11-08 | |||
JPS5971301A | 1984-04-23 | |||
JPS5968301A | 1984-04-18 | |||
JP2001072700A | 2001-03-21 | |||
JP2000288388A | 2000-10-17 | |||
JPH04158796A | 1992-06-01 | |||
JPS60232243A | 1985-11-18 | |||
JPS63270701A | 1988-11-08 | |||
JPS5971301A | 1984-04-23 | |||
JPS5968301A | 1984-04-18 | |||
JP2001072700A | 2001-03-21 | |||
JP2000288388A | 2000-10-17 |
Tadashi Takahashi
Takashi Watanabe
Suzuki Mitsuyoshi
Kazuya Nishi
Yasuhiko Murayama
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