大員環の製造方法 - F. HOFFMANN-LA ROCHE AKTIENGESELLSCHAFT

Title:

大員環の製造方法

Document Type and Number:

Japanese Patent JP5439384

Kind Code:

B2

Abstract:

The present invention relates to a new process for the preparation of macrocyclic HCV protease inhibitor compounds of the formula wherein R1 is an amino protecting group and X is halogen by way of a ring closing metathesis approach.

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Inventors:

Hirtbrandt, stephan
Puenter, Kurt
Scallone, michelangelo

Application Number:

JP2010538595A

Publication Date:

March 12, 2014

Filing Date:

December 11, 2008

Export Citation:

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Assignee:

F. HOFFMANN-LA ROCHE AKTIENGESELLSCHAFT

International Classes:

C07K5/083; A61K38/00; A61K38/55; A61P31/14; A61P43/00; C07B53/00; C07B61/00

Foreign References:

WO2007015824A2
WO2006043145A1
WO2005037214A2

Attorney, Agent or Firm:

Hajime Tsukuni
Fusayuki Saito

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