Title:
メチルコバラミンの製造法
Document Type and Number:
Japanese Patent JP4358615
Kind Code:
B2
Abstract:
The present invention provides a novel industrially excellent and ecological process for producing methylcobalamin which is useful as a medicament etc. More specifically, it provides a process for producing methylcobalamin by reducing cyanocobalamin or hydroxocobalamin in the presence of a reducing agent, and then methylating the reductant by adding a water-soluble methylating agent.
Inventors:
Yoshihiko Kubu
Tanaka Taku
Tsurui Soto
Hiroshi Kuroda
Tanaka Taku
Tsurui Soto
Hiroshi Kuroda
Application Number:
JP2003502016A
Publication Date:
November 04, 2009
Filing Date:
June 04, 2002
Export Citation:
Assignee:
Eisai R & D Management Co., Ltd.
International Classes:
C07H23/00
Domestic Patent References:
| JP45038059B1 |
Foreign References:
| WO2001042271A1 |
Other References:
Journal of Chromatography A, 1996, Vol.738, pp.43-55
BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY, 1987, Vol.9, No.1, pp.39-52
BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY, 1987, Vol.9, No.1, pp.39-52
Attorney, Agent or Firm:
Satoshi Furuya
Takahiko Mizobe
Shinji Mochida
Yoshitsune Kazumasa
Takahiko Mizobe
Shinji Mochida
Yoshitsune Kazumasa