Title:
光学活性エステルの製造法
Document Type and Number:
Japanese Patent JP5094397
Kind Code:
B2
Abstract:
A process for producing an optically active 2-hydroxybutyric ester (1), characterized by including reacting an optically active 2,3-epoxybutyric ester (2) with a thiol in the presence of scandium trifluoromethanesulfonate or ytterbium trifluoromethanesulfonate, to thereby produce Compound (3), and subjecting Compound (3) to desulfurization reaction:
(wherein R represents a C1 to C6 alkyl group or a C7 or C8 aralkyl group; R 1 represents a C1 to C12 alkyl group or a phenyl group; and * represents S- or R-absolute configuration). The present invention provides a process for producing an optically active 2-hydroxybutyric ester at high yield and high optical purity.
Inventors:
Takaaki Araki
Yuko Yamazaki
Shibuya Kimiyuki
Yuko Yamazaki
Shibuya Kimiyuki
Application Number:
JP2007532175A
Publication Date:
December 12, 2012
Filing Date:
August 24, 2006
Export Citation:
Assignee:
Kowa Co., Ltd.
International Classes:
C07C67/317; C07C69/675; C07C319/14; C07C323/52; C07B53/00; C07B61/00
Domestic Patent References:
| JPH0436195A | 1992-02-06 |
Attorney, Agent or Firm:
Alga Patent Office, a patent business corporation
Miyuki Ariga
Toshio Takano
Toshio Nakajima
Masaki Murata
Hiroto Yamamoto
Miyuki Ariga
Toshio Takano
Toshio Nakajima
Masaki Murata
Hiroto Yamamoto