Title:
プロスタグランジン類の製造方法
Document Type and Number:
Japanese Patent JP4153998
Kind Code:
B2
Abstract:
A hydroxy-1-alkyne is reacted with a tin hydride compound, and the obtained (E,Z)-hydroxyvinylstannanes are separated to give the (E)-substance which is further converted to a vinylcopper complex shown by followed by the conjugate addition reaction with an alpha , beta -unsaturated cyclopentenone, and the deprotecting reaction is subsequently carried out to prepare a prostaglandin or an intermediate of prostaglandins easily, efficiently and industrially favorably.
Inventors:
Noriaki Murata
Aramata Atsushi
Sadayoshi Takeuchi
Aramata Atsushi
Sadayoshi Takeuchi
Application Number:
JP52239898A
Publication Date:
September 24, 2008
Filing Date:
November 14, 1997
Export Citation:
Assignee:
Daiichi Fine Chemical Co., Ltd.
International Classes:
C07C405/00; C07F1/08; C07F7/22
Domestic Patent References:
| JP59210065A | ||||
| JP63316786A | ||||
| JP53108929A | ||||
| JP2255654A | ||||
| JP61087638A | ||||
| JP6092930A |
Attorney, Agent or Firm:
Kiyoji Kuzuwa