Title:
ステロイド系のチゴゲニンを基に合成した安息香酸ヒドラゾンの医学的適用
Document Type and Number:
Japanese Patent JP2011521005
Kind Code:
A
Abstract:
Novel benzoic acid hydrazones of 5alpha-androstan-3,17-dione have been prepared on the basis of steroidal tigogenin of the plant Yucca gloriosa. The hydrazones of the General Formula (I), General Formula (II) and General Formula (III) as shown in the accompanying FIGURE of the drawing are synthesized. The hydrazones have shown promising anti-T.B., anti-cancer and anti-HIV activity revealing immense potential as more efficacious, less toxic drugs with fewer undesirable side effects. They could also prove valuable in correcting hormonal abnormalities that cause severe health problems.
Inventors:
Scheller, Ashok, Langanas
Melani, Myr
Scherrer, Millind
Amirana Siviri, Rera
Scherrer, Balkhishna
Melani, Myr
Scherrer, Millind
Amirana Siviri, Rera
Scherrer, Balkhishna
Application Number:
JP2011511166A
Publication Date:
July 21, 2011
Filing Date:
March 03, 2009
Export Citation:
Assignee:
Scheller, Ashok, Langanas
Melani, Myr
Scherrer, Millind
Amirana Siviri, Rera
Scherrer, Balkhishna
Melani, Myr
Scherrer, Millind
Amirana Siviri, Rera
Scherrer, Balkhishna
International Classes:
C07J1/00; A61K31/568; A61P3/06; A61P3/10; A61P31/06; A61P31/18; A61P35/00
Attorney, Agent or Firm:
Ikeda adult
Kazuhiro Yamaguchi
Masakazu Noda
Kazuhiro Yamaguchi
Masakazu Noda