To provide new medicaments comprising a sialic acid derivative, especially a low-molecular sialic acid derivative, and more concretely to provide a prophylactic and/or therapeutic agent for viral disease such as influenza virus infection disease.
The medicaments comprise a compound represented by formula I {wherein R1 is a 1-6C alkyl group; R2 is a (substituted) phenyl group, a 1-20C alkyl group, a 1-20C alkenyl group or (CH2)k-[NH-(CH2)m-NH]n-Y (wherein Y is phoshatidyl ethanolamine residue, polyglutamic acid residue or the like; k and m are each an integer of 2 to 10); R3 is H or a (substituted) hydroxy group; R4 is H, a halogen, azido group, a (substituted) amino group or a (substituted) hydroxy group; and R5 to R8 are each a (substituted) hydroxy group} or its pharmacologically permissive salt as an active component.
CHI-WAY WONG
SUZUKI YASUO
