PURPOSE: To obtain a medicinal composition having a high ratio of attaining to vehicula and a high utilization ratio of an active ingredient, and useful as an antiasthmatic agent by blending fine powder of a specific steroid derivative with lactose.

CONSTITUTION: This medicinal preparation is obtained by blending a crystal obtained by adding (iii) an aggregating solvent for aggregation and precipitation to (ii) a suspension liquid of (i) fine powder of methyl (+)-9α-chloro-6α- fluoro-11β-hydroxy-16α-methyl-3-oxo-17α-propionyloxyandrosta-1,4-diene-17β- carboxylate of the formula, with (B) a lactose (e.g. ≥4 fold amount based on the component A). Furthermore, it is preferable that combinations of the component (ii) with the component (iii) are such that the component (ii) is water and the component (iii) is ethyl acetate, the component (ii) is water containing acetone and the component (iii) is ethyl acetate, or the component (ii) is hexane containing acetone and the component (iii) is water.