To provide a medicine for inflammatory respiratory illness which contains vitamin D3 derivative(s) or pharmaceutically acceptable solvate(s) thereof as an active ingredient and has an effect of suppressing the neutrophile permeation.
This medicine is obtained by incorporating, in effective amount(s) for therapy, one or more vitamin D3 derivative(s) or pharmaceutically acceptable solvate(s) thereof selected from a group comprising (1) 1α- hydroxyvitamin D3, (2) 1α,24(R)-dihydroxyvitamin D3, (3) 1α,25-dihydroxyvitamin D3, (4) 1α,24,25-trihydroxyvitamin D3, (5) 24,24-difluoro-1α,25-dihydroxyvitamin D3, (6) 26,26,26,27,27,27-hexafluoro-1α,25-dihydroxyvitamin D3, (7) 22-oxa-1α,25- dihydroxyvitamin D3, (8) 22-dehydro-1α,24(S)-dihydroxyvitamin D3-25,26,27-cyclopropane, (9) 20-epi-22-oxa-24a,26a,27a-trihomo-1α,25- dihydroxyvitamin D3, etc.
MIHASHI HIROAKI
OTA TOMOHIRO
HAMAMURA ICHIRO
TAKANO YASUHIRO
