To arouse a patient's interest in a medicine instruction to prevent forgetting to pass an eye over the instruction or receive it by indicating free information given by an issue institution of a medical institution, a drugstore, or the like in addition to a patient's personal information and medicine information on the medicine instruction, and indicating the medicine instruction on a medicine bag, or the like.

In using a preparation system 2 for a medicine instruction, medicine instructions information such as a name, effect, how to use and so on are previously computerized with a photo of an external form to be stored in a storage device 14. A keyboard 18, a disc device 19 and an image take-in device 20 may be used to input information every time. In the medical institution and a drugstore, the contents of prescription and personal information such as the age, the distinction of sex of a patient, and the name of a medicine taken at present is input with free information formed by guide information, advertisement and the like by an input device 12, and an input signal for selecting the stored medicine information is input to an input circuit 17. After that, a required output signal is transmitted to an output circuit 21 to prepare a medicine instruction by a color printer 13.