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Title:
MEDICINE FOR REINFORCING TREATING EFFECT ON EDEMA
Document Type and Number:
Japanese Patent JPH10251161
Kind Code:
A
Abstract:

To obtain the subject medicine capable of reinforcing the edema- treating effect of a diuretic medicine by simultaneously using human serum albumin prepared by genetic operations together with the diuretic medicine.

This medicine contains (A) human serum albumin (hereinafter rHSA) prepared by genetic operations as an active ingredient, and can reinforce the edema-treating effect of (B) a diuretic medicine. The component A is prepared by using a rHSA-producing bacterium, an animal cell, etc., especially a yeast as host, in particular, a yeast belonging to the genus Saccharomyces or Pichia through genetic operations. Thereby, it can be expected that treating effects on nephrotic syndrome, kidney diseases, etc., are reinforced.


Inventors:
NIITOME MASAKAZU
MATSUI TOMOHIKO
MARUYAMA TOMOYUKI
TSUCHIYAMA HIROMI
TSUKADA MINORU
Application Number:
JP5644897A
Publication Date:
September 22, 1998
Filing Date:
March 11, 1997
Export Citation:
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Assignee:
GREEN CROSS CORP
International Classes:
C12N15/09; A61K38/16; A61P3/00; A61P43/00; (IPC1-7): A61K38/16; A61K38/16
Domestic Patent References:
JPH08116985A1996-05-14
JPH04352727A1992-12-07
JPH01311027A1989-12-15
JPH01305036A1989-12-08
JPS61271226A1986-12-01
Other References:
DAVISON,A.M. ET AL: "Salt-poor human albumin in management of nephrotic syndrome", BR. MED. J., vol. 1, no. 5906, JPN4007011463, 1974, pages 481 - 4, ISSN: 0000847646
津留 徳 他: "小児ネフローゼ症候群に対するアルブミン20%(化血研)の使用経験", 臨床と研究, vol. 58巻12号, JPN4007011464, 1981, pages 251 - 255, ISSN: 0000847647
Attorney, Agent or Firm:
Takashima Hajime