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Title:
MELAMINE-AGGREGATING HORMONE ANTAGONIST
Document Type and Number:
Japanese Patent JP2002241274
Kind Code:
A
Abstract:

To provide a melamine-aggregating hormone antagonist which is useful as a medicine for preventing and treating obesity.

This melamine-aggregating hormone antagonist contains a compound represented by the formula [Ar1 is a cyclic group which may have one or more substituents; X and Y are each identically or differently a 1 to 6C spacer for the main chain; Ar is a condensed polycyclic aromatic ring which may have one or more substituents; R1 and R2 are each identically or differently H or a hydrocarbon group which may have one or more substituents, or R1 and R2 may form together with the adjacent nitrogen atom a nitrogen-containing heterogeneous ring which may have one or more substituents; R2 may form together with the adjacent nitrogen atom and Y a nitrogen-containing heterogeneous ring which may have one or more substituents; and R2 may further form a condensed ring together with the adjacent nitrogen atom, Y and Ar] or its salt.


Inventors:
ISHIHARA YUJI
SUZUKI NOBUHIRO
TAKEKAWA SHIRO
Application Number:
JP2001132357A
Publication Date:
August 28, 2002
Filing Date:
April 27, 2001
Export Citation:
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Assignee:
TAKEDA CHEMICAL INDUSTRIES LTD
International Classes:
C07D295/12; A61K31/167; A61K31/402; A61K31/403; A61K31/404; A61K31/4418; A61K31/4427; A61K31/443; A61K31/4439; A61K31/445; A61K31/4453; A61K31/454; A61K31/455; A61K31/47; A61K31/4709; A61K31/4725; A61K31/4745; A61K31/496; A61K31/5375; A61K31/5377; A61P3/04; A61P3/10; A61P9/10; A61P9/12; A61P43/00; C07C233/80; C07C237/48; C07D209/14; C07D211/16; C07D213/82; C07D215/48; C07D401/06; C07D401/12; C07D401/14; C07D405/12; C07D417/06; C07D487/04; (IPC1-7): A61K31/167; A61K31/402; A61K31/404; A61K31/4439; A61K31/445; A61K31/4453; A61K31/454; A61K31/455; A61K31/47; A61K31/4709; A61K31/4725; A61K31/4745; A61K31/496; A61K31/5377; A61P3/04; A61P3/10; A61P9/10; A61P9/12; A61P43/00; C07C233/80; C07C237/48; C07D209/14; C07D211/16; C07D213/82; C07D215/48; C07D295/12; C07D401/06; C07D401/12; C07D401/14; C07D405/12; C07D417/06; C07D487/04
Attorney, Agent or Firm:
Sekiguchi Yo (1 person outside)