Title:
ビニルフルオロアルカンスルホナート化合物の製造方法
Document Type and Number:
Japanese Patent JP7017229
Kind Code:
B2
Abstract:
To provide a method for producing 3,3,3-trifluoromethyl-1-arylalken-1-yltrifluoromethane sulfonate and an analog thereof, as a building block useful for development of pharmaceuticals, agrochemicals and the like, at a low cost and without using transition metal catalysts.SOLUTION: The present invention provides a method for producing a vinyl fluoroalkane sulfonate compound represented by formula (III), including reacting an alkyne compound such as 1-phenyl-1-hexyne with a fluoroalkane sulfonic acid anhydride in the presence of a polycyclic tertiary amine and acetonitrile [in the formula, each R independently represents a hydrogen atom, a C1-C10 alkyl group or the like: Ris a C1-C10 fluoroalkyl group; and the wavy line represents either a trans or cis configuration, or a mixture thereof).SELECTED DRAWING: None
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Inventors:
Takuji Kawamoto
Junya Mitsui
Akio Uemura
Junya Mitsui
Akio Uemura
Application Number:
JP2017217052A
Publication Date:
February 08, 2022
Filing Date:
November 10, 2017
Export Citation:
Assignee:
Yamaguchi University
International Classes:
C07C303/26; C07C309/65
Other References:
Tomita, Ren 他,Photoredox-Catalyzed Stereoselective Conversion of Alkynes into Tetrasubstituted Trifluoromethylated Alkenes,Angewandte Chemie, International Edition ,2015年,54(44),12923-12927
Wang, Xi 他,Regio- and Stereoselective Radical Perfluoroalkyltriflation of Alkynes Using Phenyl(perfluoroalkyl)iodonium Triflates,Organic Letters,2017年05月,19(11),2977-2980
Nenajdenko, Valentine G. 他,Synthesis of β-dimethylsulfonium- and β-methylthio-substituted vinyl triflates by reaction of acetylenes with dimethyl sulfide ditriflate,Synthesis,1997年,(3),351-355
Wang, Xi 他,Regio- and Stereoselective Radical Perfluoroalkyltriflation of Alkynes Using Phenyl(perfluoroalkyl)iodonium Triflates,Organic Letters,2017年05月,19(11),2977-2980
Nenajdenko, Valentine G. 他,Synthesis of β-dimethylsulfonium- and β-methylthio-substituted vinyl triflates by reaction of acetylenes with dimethyl sulfide ditriflate,Synthesis,1997年,(3),351-355
Attorney, Agent or Firm:
Hiroki Masaki
Seiji Ozawa
Yusaku Tokai
Kazuhiro Matsuda
Horiuchi Makoto
Masako Yamauchi
Shuichi Sonomoto
Akihiro Yamamura
Satoshi Morikawa
Hiroyuki Tomita
Seiji Ozawa
Yusaku Tokai
Kazuhiro Matsuda
Horiuchi Makoto
Masako Yamauchi
Shuichi Sonomoto
Akihiro Yamamura
Satoshi Morikawa
Hiroyuki Tomita