PURPOSE: To increase the vitamin E content in an algal body in cultivating an alga of the genus Euglena having the biosynthetic ability of tocopherol in a culture medium to produce the algal body containing the vitamin E, by adding a specific organic compound to the culture medium.
CONSTITUTION: One or more organic compounds selected from shikimic acid, prephenic acid, chorismic acid, phenylpyruvic acid, L-phenylalanine, L-tyrosine, p-hydroxyphenylpyruvic acid, homogentisic acid and homoarbutin are added to a nutrient culture medium consisting of a carbon source, nitrogen source, inorganic salts, etc. The amount of the organic compounds to be added is suitably about 0.01W2%. An alga of the genus Euglena, e.g. Euglena gracilis Z strain or Euglena viridis, having the biosynthetic ability of tocopherol is cultivated in the resultant culture medium to give the aimed algal body of the genus Euglena containing vitamin E useful as a health drug in a high concentration.
NAKANO OSAHISA
SHIGEOKA SHIGERU
TAKETOMI HIDETOSHI
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