Title:
METHOD OF ENHANCING DELIVERY OF THERAPEUTIC COMPOUNDS TO EYE
Document Type and Number:
Japanese Patent JP2019055980
Kind Code:
A
Abstract:
To provide methods for enhancing the delivery of a therapeutic agent to an eye of a subject.SOLUTION: A method of enhancing the delivery of a therapeutic agent to an eye of a subject comprises the step of administering a plasmin or derivative thereof and the therapeutic agent to the eye. The therapeutic agent is selected from a nucleic acid, a small molecule, an antibody, a peptide and the like.SELECTED DRAWING: Figure 1
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Inventors:
PAN XHUO-HUA
ELENA IVANOVA
ELENA IVANOVA
Application Number:
JP2018228150A
Publication Date:
April 11, 2019
Filing Date:
December 05, 2018
Export Citation:
Assignee:
UNIV WAYNE STATE
International Classes:
A61K47/42; A61K9/127; A61K9/50; A61K9/51; A61K31/7088; A61K31/712; A61K31/713; A61K35/76; A61K38/00; A61K38/02; A61K39/395; A61K45/00; A61K48/00; A61P27/02
Domestic Patent References:
| JP2009527580A | 2009-07-30 | |||
| JP2009536219A | 2009-10-08 | |||
| JP2006518708A | 2006-08-17 | |||
| JP2012532596A | 2012-12-20 |
Foreign References:
| WO2011023805A1 | 2011-03-03 | |||
| WO2007005856A1 | 2007-01-11 | |||
| WO2009067407A2 | 2009-05-28 |
Attorney, Agent or Firm:
Hatsushi Shimizu
Masao Haruna
Hirotaka Yamaguchi
Toshi Gobe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Masato Ozeki
Yoshihiro Igarashi
Kazuya Kawamoto
Masao Haruna
Hirotaka Yamaguchi
Toshi Gobe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Masato Ozeki
Yoshihiro Igarashi
Kazuya Kawamoto