腸内細菌科の細菌を用いてアルコール類およびアミン類を酵素によりスルフリル化する方法

Title:

腸内細菌科の細菌を用いてアルコール類およびアミン類を酵素によりスルフリル化する方法

Document Type and Number:

Japanese Patent JP7424320

Kind Code:

B2

Abstract:

A method for enzymatic sulfurylation of a substrate is provided which includes the steps of reacting the substrate with 3′-phosphoadenosine-5′-phosphosulfate (PAPS) in a medium containing a bacterium belonging to the family Enterobacteriaceae to produce a sulfated derivative of the substrate, and collecting the sulfated derivative from the medium, wherein the bacterium has been modified to produce, at least, a protein having sulfotransferase activity, and to attenuate expression of an aphA gene, a cysQ gene, or a cpdB gene, or a combination of these.

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Inventors:

Smirnov, Sergei Vasilyevich
Tokmakova, Irina Lvovna

Application Number:

JP2020569215A

Publication Date:

January 30, 2024

Filing Date:

July 11, 2019

Export Citation:

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Assignee:

AJINOMOTO CO.,LTD.

International Classes:

C12P11/00; C12N15/09; C12P19/04

Domestic Patent References:

JP2003265194A
JP2002530087A

Foreign References:

US20090197308

Attorney, Agent or Firm:

Sakai International Patent Office

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