Title:
METHOD FOR ENZYMICALLY SYNTHESIZING AMINO ACID OLIGOMER HAVING SINGLE MOLECULAR WEIGHT
Document Type and Number:
Japanese Patent JPH03183495
Kind Code:
A
Abstract:
PURPOSE: To obtain an amino acid oligomer, having a homogeneous polymerization degree and suitable for biocompatible materials, etc., in one pot by using a protease as a catalyst in producing the amino acid oligomer having a single molecular weight from an amino acid derivative.
CONSTITUTION: A protease (e.g. chymotrypsin) is reacted with one or more amino acid derivatives as a substrate in a buffer solution (preferably at pH2-10) and formed precipitated are then separated by filtration, washed and dried to afford an amino acid oligomer having a single molecular weight.
Inventors:
RI HIROKI
FUKUSHI HIDEAKI
UCHINO MASAZUMI
OYAMA KAORU
FUKUSHI HIDEAKI
UCHINO MASAZUMI
OYAMA KAORU
Application Number:
JP24943889A
Publication Date:
August 09, 1991
Filing Date:
September 26, 1989
Export Citation:
Assignee:
CHISSO CORP
International Classes:
C12P21/02; (IPC1-7): C12P21/02
Domestic Patent References:
| JPS6455192A | 1989-03-02 | |||
| JPS6246559A | 1987-02-28 | |||
| JPS587278A | 1983-01-17 |
Attorney, Agent or Firm:
Yataro Sasai (1 person outside)