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Title:
ヒト悪性卵巣胚細胞腫瘍の細胞株の樹立方法、ヒト悪性卵巣胚腫瘍細胞株、及びその利用
Document Type and Number:
Japanese Patent JP5098013
Kind Code:
B2
Abstract:

To provide a method for establishing cell strain derived from human malignant ovarian germ cell tumor and to provide the cell strain and to provide a method or the like for screening an antineoplastic agent by utilizing the cell strain.

The present invention provides a tumor cell strain obtained by passing through a step for culturing human malignant ovarian germ cell tumor cell in a culture medium containing a serum, insulin and epidermal growth factor (EGF), its carboplatin and cisplatin-resistant cell strain and provides a method for screening a compound effective in human yolk sac tumor using a transfer factor Nkx 2.5 as a target molecule by using the cell strain.

COPYRIGHT: (C)2007,JPO&INPIT


Inventors:
Yoshikawa Fumitaka
Kiyozumi Shibata
Application Number:
JP2006337852A
Publication Date:
December 12, 2012
Filing Date:
December 15, 2006
Export Citation:
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Assignee:
Nagoya University
International Classes:
C12N5/09; A61K45/00; A61P35/00; C12N5/07; C12N5/073; C12N15/09; C12N15/113; C12Q1/02; G01N33/15; G01N33/50
Other References:
Acta Histochemica et Cytochemica,1992年,Vol.25,p.563-576
In Vitro Cell Dev Biol.,1992年,Vol.28A,p.449-454
J Cell Biol.,1980年,Vol.86,p.483-489
Int J Cell Cloning.,1983年,Vol.1,p.216-229
Lab Invest.,2004年,Vol.84,p.923-931
Attorney, Agent or Firm:
Mikiharu Hagino