Title:
低置換度ヒドロキシプロピルセルロース粒子の形成方法
Document Type and Number:
Japanese Patent JP3552160
Kind Code:
B2
Abstract:
An object of the present invention is to provide a process for the production of low-substituted hydroxypropyl cellulose wherein, in the formation of low-substituted hydroxypropyl cellulose particles, a granular material obtained by granulating the reaction product is neutralized with an acid to form neutralization-precipitated particles of low-substituted hydroxypropyl cellulose which can reduce the treating time as compared with conventional processes and, moreover, permit its ash content to be easily decreased in a subsequent washing step. Specifically, the reaction product of an alkali cellulose with a hydroxypropylating agent is granulated, and the resulting granular material is neutralized with an acid.
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Inventors:
Naosuke Maruyama
Hiroshi Umezawa
Hiroshi Umezawa
Application Number:
JP2000005167A
Publication Date:
August 11, 2004
Filing Date:
January 14, 2000
Export Citation:
Assignee:
Shin-Etsu Chemical Co., Ltd.
International Classes:
A61K47/38; A61J3/02; A61K9/14; C08B11/08; C08B11/20; (IPC1-7): C08B11/08; A61J3/02
Attorney, Agent or Firm:
Shoichi Okuyama
Arihara Koichi
Matsushima Tetsuo
Arihara Koichi
Matsushima Tetsuo