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Title:
METHOD FOR MANUFACTURING AMINO ACID FLUORIDE DERIVATIVE
Document Type and Number:
Japanese Patent JP2002145846
Kind Code:
A
Abstract:

To provide an efficient method for manufacturing an amino acid fluoride derivative which method has an excellent yield and a high fluorine utilization efficiency.

The method for manufacturing an amino acid fluoride derivative, for example, a compound of general formula 3 or 7 (R1 and R2 are each independently the residue of a natural or non-natural amino acid; X and Y are each independently H or a protecting group for an amino group; and n is an integer of 1-4) by reacting an amino acid derivative with an imidazoline derivative expressed by general formula 1 (R1 and R2 are each a lower alkyl).


Inventors:
KOMATSU HIRONORI
NARUSE JUNKO
Application Number:
JP2000341981A
Publication Date:
May 22, 2002
Filing Date:
November 09, 2000
Export Citation:
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Assignee:
MITSUI CHEMICALS INC
International Classes:
C07C269/06; C07C229/18; C07C271/22; (IPC1-7): C07C269/06; C07C229/18; C07C271/22
Domestic Patent References:
JP2000038370A2000-02-08
JPS6470450A1989-03-15
JP2000038370A2000-02-08
JPS6470450A1989-03-15
Other References:
JPN6010033737, J.Org.Chem, 19910412, Vol.56, No.8, p2611−2614
JPN6010033738, J.Am.Chem.Soc., 19901219, Vol.112, No.26