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Title:
METHOD OF MEASURING IMMUNITY FOR TYPE-II SHIGELLA-LIKE TOXIN IN HUMAN BLOOD, AND KIT THEREFOR
Document Type and Number:
Japanese Patent JP2003139774
Kind Code:
A
Abstract:

To highly sensitively measure a type-II Shigella-like toxin in a human blood.

Immunoreaction is carried out under the presence of calcium ions added, when immunity of the type-II Shigella-like toxin in the human blood is measured using the immunoreaction of the type-II Shigella-like toxin in the human blood with an antibody to a B sub-unit of the type-II Shigella-like toxin or an antigen-coupling fragment thereof. The immunity measurement of the type-II Shigella-like toxin SLT-II in the human blood is realized by adding the calcium ions Ca2+ in a reaction solution. A clinical morbid state of a patient infected by enteric hemorrhagic Escherichia coli is grasped by evaluating a SLT-II concentration in the human blood, in the present invention, a data useful for reference to a therapeutical policy is provided thereby, and it is very effective on clinical application.


Inventors:
YAMAGAMI SHINSUKE
MOTOKI MASAMICHI
KIMURA TAKESHI
KAWAMURA TAKASHI
MATSUMOTO YOICHI
TETSUMOTO TORU
SAKURAI MASAAKI
HARADA HIROTOMO
OKA MASANORI
Application Number:
JP2001333130A
Publication Date:
May 14, 2003
Filing Date:
October 30, 2001
Export Citation:
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Assignee:
TEIJIN LTD
SRL INC
International Classes:
G01N33/53; G01N33/531; G01N33/569; (IPC1-7): G01N33/53; G01N33/531; G01N33/569
Attorney, Agent or Firm:
Eijiro Tanigawa