METHOD FOR PREDICTING BREAST CANCER PROGNOSIS

Japanese Patent JP2017055769

A

PROBLEM TO BE SOLVED: To provide biomarkers associated with breast cancer prognosis.SOLUTION: The present invention provides biomarkers that include coding transcripts and their expression products, as well as non-coding transcripts, and are useful for predicting the likelihood of breast cancer recurrence in a breast cancer patient. The present invention also provides a novel method for identifying intergenic sequences that correlate with a clinical outcome. The present invention further provides a method for predicting a likelihood of long-term survival without recurrence of breast cancer in a breast cancer patient. The method comprises determining a level of one or more RNA transcripts, or its expression product, in a breast cancer tumor sample obtained from the patient.SELECTED DRAWING: None

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JOFFRE B BAKER
DOMINICK V SINICROPI
ROBERT J PELHAM
MICHAEL CRAGER
FRANCOIS COLLIN
JAMES C STEPHANS
LIU MEI-LAN
JOHN MORLAN
QU KUNBIN

JP2016252390A

March 23, 2017

December 27, 2016

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GENOMIC HEALTH INC

C12Q1/68; C12N15/09; G01N33/53; G01N33/68; G01N37/00; G16B20/00

WO2011120984A1	2011-10-06
WO2009071655A2	2009-06-11
WO2005001138A2	2005-01-06
WO2009033941A1	2009-03-19

CLIN. CANCER RES., vol. Vol. 17, No. 18, JPN6017038649, 15 September 2011 (2011-09-15), pages p. 6012-6020
CLIN. CANCER RES., vol. Vol. 14, No. 6, JPN6017038650, 2008, pages p. 1744-1752
CLIN. CANCER RES., vol. Vol. 16, No. 15, JPN6017038651, 2010, pages p. 3860-3874

Hidesaku Yamamoto
Natsuki Morishita

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