Title:
パモ酸ピルビニウム及びその結晶形態の調製方法
Document Type and Number:
Japanese Patent JP7021107
Kind Code:
B2
Abstract:
The present invention relates to a process for the preparation of pyrvinium pamoate, which comprises reacting pyrvinium methyl sulphate salt of formula (II) with disodium pamoate of formula (III), in the presence of a base; to processes for the preparation of crystalline Form A and crystalline Form III of pyrvinium pamoate; as well as a process for the purification of crystalline Form III. It also relates to crystalline Forms A and III of pyrvinium pamoate and to pharmaceutical compositions containing them.
Inventors:
Del Rio Pelicacho, Jose Luis
Marti Via, Giuseppe
Canovas Paredes, Antonio de Padua
Marti Via, Giuseppe
Canovas Paredes, Antonio de Padua
Application Number:
JP2018553220A
Publication Date:
February 16, 2022
Filing Date:
April 12, 2017
Export Citation:
Assignee:
Ulkima, Sociedad Anonima
International Classes:
C07D401/06; A61K31/4709; A61P33/00; C07C65/11
Domestic Patent References:
| JP2008527047A |
Foreign References:
| US2925417 | ||||
| US2515912 |
Other References:
高田則幸,創薬段階における原薬Formスクリーニングと選択,PHARM STAGE,Vol.6, No.10,2007年01月15日,p.20-25
Attorney, Agent or Firm:
Hiroe Associates Patent Office
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