Title:
METHOD FOR PREVENTING CRYSTAL GROWTH AND PARTICLE AGGLOMERATION IN NANOPARTICLE COMPOSITION
Document Type and Number:
Japanese Patent JP2010031026
Kind Code:
A
Abstract:
To provide a method for preventing crystal growth and particle agglomeration in a nanoparticle composition in heating or storage.
The method is for forming a nanoparticle composition which makes an optimal effective average particle size thereof about 150 nm to about 350 nm and is for a poorly soluble drug having one or plurality of non-crosslinking surface stabilizer(s) adsorbed on the surface of drug, wherein at least one of the at least one or plurality of the surface stabilizer(s) used here is a polyoxyethylene sorbitan fatty acid ester.
Inventors:
LIVERSIDGE ELAINE
GOTTARDY GRETA A
WEI LINDEN
GOTTARDY GRETA A
WEI LINDEN
Application Number:
JP2009223800A
Publication Date:
February 12, 2010
Filing Date:
September 29, 2009
Export Citation:
Assignee:
ELAN PHARMA INT LTD
International Classes:
A61K9/14; A61K47/14
Attorney, Agent or Firm:
Hatsushi Shimizu
Toshi Gobe
Koichi Niimi
Tomohiko Kobayashi
Shinichi Watanabe
Ryuichi Inoue
Masato Ozeki
Toshi Gobe
Koichi Niimi
Tomohiko Kobayashi
Shinichi Watanabe
Ryuichi Inoue
Masato Ozeki
Previous Patent: JP2010031025
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