Title:
1,3―ジオキソラン―4―メタノール化合物の製造法
Document Type and Number:
Japanese Patent JP3822644
Kind Code:
B2
Abstract:
A process for preparing easily and economically a 1,3-dioxolane-4-methanol compound in a racemic form or an optically active form with high purity and in high yield. The process comprises reacting an alkali metal or alkaline earth metal salt of an alcohol or a carboxylic acid with a halogenomethyl-1,3-dioxolane which is prepared by acetalizing a halogeno-1,2-propanediol of a formula (1) wherein X is a halogen atom, in an acid catalyst to conduct esterification or etherification, and then hydrolyzing the ester group and hydrogenolyzing the ether group to prepare a 1,3-dioxolane-4-methanol compound of a formula (5) wherein R<1> and R<2> are hydrogen atom, alkyl having 1 to 4 carbon atoms or phenyl, and R<1> and R<2> may form a cycloalkyl ring having 3 to 6 carbon atoms with the adjacent carbon atoms.
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Inventors:
Kazumasa Higami
Yoshiro Furukawa
Yoshiro Furukawa
Application Number:
JP51348598A
Publication Date:
September 20, 2006
Filing Date:
September 09, 1997
Export Citation:
Assignee:
Daiso Co., Ltd.
International Classes:
C07D317/20; C07D317/22
Other References:
Vassilia Partali et al, Tetrahedron Asymmetry, 1992年,Vol.3,No.1, 65-72
Attorney, Agent or Firm:
Aoyama Aoi
Kyousei Tamura
Yushiro Tsuboi
Kyousei Tamura
Yushiro Tsuboi