Title:
1,3-オキサチオランヌクレオチドの製造方法
Document Type and Number:
Japanese Patent JP5203897
Kind Code:
B2
Abstract:
Processes for the preparation of 1,3-oxathiolane nucleosides are provided that include efficient methods for the preparation of the 1,3-oxathiolane ring and subsequent condensation of the 1,3-oxathiolane with a pyrimidine or purine base. Using the processes described herein, the compounds can be provided as isolated enantiomers.
Inventors:
Painter, George Earl.
Riotta, Dennis Sea.
Almond, Merrick
Clary, Daryl
Soria, Jose
Snydman, Marcos Lewis
Riotta, Dennis Sea.
Almond, Merrick
Clary, Daryl
Soria, Jose
Snydman, Marcos Lewis
Application Number:
JP2008291234A
Publication Date:
June 05, 2013
Filing Date:
November 13, 2008
Export Citation:
Assignee:
The Reed Sciences, Inc.
Emory University
Emory University
International Classes:
C07D411/04; A61K31/505; C07D319/06; C07D327/04; C07D473/00
Domestic Patent References:
| JP10147586A | ||||
| JP10502615A | ||||
| JP5505794A | ||||
| JP4249393B2 |
Foreign References:
| US5204466 | ||||
| WO1997021706A1 |
Attorney, Agent or Firm:
Atsushi Aoki
Takashi Ishida
Jun Tsuruta
Fukumoto product
Tetsuji Koga
Kazuhiro Nakamura
Yoichi Watanabe
Masaru Nakajima
Tetsuji Koga
Kazuhiro Nakamura
Yoichi Watanabe
Masaru Nakajima
Takashi Ishida
Jun Tsuruta
Fukumoto product
Takashi Ishida
Jun Tsuruta
Fukumoto product
Tetsuji Koga
Kazuhiro Nakamura
Yoichi Watanabe
Masaru Nakajima
Tetsuji Koga
Kazuhiro Nakamura
Yoichi Watanabe
Masaru Nakajima
Takashi Ishida
Jun Tsuruta
Fukumoto product