Title:
２，３−ビスホスフィノピラジン誘導体の製造方法及びホスフィン遷移金属錯体の製造方法
Document Type and Number:
Japanese Patent JP6641328
Kind Code:
B2
Abstract:
A production method for a 2,3-bisphosphinopyrazine derivative, characterized by including a first step, in which a base is added to and reacted with a liquid containing a 2,3-dihalogenopyrazine represented by general formula (1), a hydrogen-phosphine borane compound represented by general formula (2), and an agent for borane elimination to obtain a 2,3-bisphosphinopyrazine derivative represented by general formula (3). The present invention can provide an industrially advantageous method for producing the 2,3-bisphosphinopyrazine derivative.
Inventors:
Tsuneo Imamoto
Application Number:
JP2017153422A
Publication Date:
February 05, 2020
Filing Date:
August 08, 2017
Export Citation:
Assignee:
Nippon Chemical Industry Co., Ltd.
International Classes:
C07F9/6509; C07F1/12
Domestic Patent References:
| JP200756007A |
Foreign References:
| WO2011129365A1 | ||||
| CN102464675A |
Other References:
IMAMOTO Tsuneo et al.,An Air-Stable P-Chiral Phosphine Ligand for Highly Enantioselective Transition-Metal-Catalyzed React,Journal of the American Chemical Society,2005年,127,11934-11935
LIU Yang et al.,A new and convenient approach for the synthesis of P-stereogenic intermediates bearing a tert-butyl(,Research on Chemical Intermediates,2017年 4月 7日,43(8),4959-4966,ISSN 0922-6168
LIU Yang et al.,A new and convenient approach for the synthesis of P-stereogenic intermediates bearing a tert-butyl(,Research on Chemical Intermediates,2017年 4月 7日,43(8),4959-4966,ISSN 0922-6168
Attorney, Agent or Firm:
Patent Business Corporation Ashitaba International Patent Office