Title:
エポチロンのC1-C15-フラグメント及びその誘導体の生成方法
Document Type and Number:
Japanese Patent JP2009513498
Kind Code:
A
Abstract:
This invention describes a process for the production of C1-C15-fragments of epothilones and derivatives thereof, in which a C1-C6-fragment is linked with a C7-C12-fragment to a C1-C12-fragment, and the latter then is reacted with a C13-15-fragment to form the C1-C15 initial epothilone product that is to be produced. The thus obtained C1-C15 initial epothilone products can be reacted according to known methods to form the actual active ingredients. In addition, the invention relates to the corresponding C1-C12-fragments.
Inventors:
Clar, Ulrich
Buchmann, Bernd
Schwede, Wolfgang
Sukhbara, Berner
Buchmann, Bernd
Schwede, Wolfgang
Sukhbara, Berner
Application Number:
JP2006518018A
Publication Date:
April 02, 2009
Filing Date:
June 19, 2004
Export Citation:
Assignee:
Bayer Schering Pharma Aktiengesellschaft
International Classes:
C07D313/00; C07C45/67; C07C49/17; C07D225/00; C07D281/00; C07D319/06; C07D417/06; C07D493/04; C07F7/18
Domestic Patent References:
| JP2001512723A | 2001-08-28 |
Attorney, Agent or Firm:
Atsushi Aoki
Takashi Ishida
Fukumoto product
Tetsuji Koga
Kazuhiro Nakamura
Masaya Nishiyama
Takashi Ishida
Fukumoto product
Tetsuji Koga
Kazuhiro Nakamura
Masaya Nishiyama