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Title:
N−カルバモイル−tert−ロイシンの製造法
Document Type and Number:
Japanese Patent JP5647790
Kind Code:
B2
Abstract:
The present invention relates to a process for producing an N-carbamoyl-tert-leucine, characterized in mixing tert-leucine with an isocyanic acid compound while a pH of the mixture is kept at not less than 8.0 and not more than 13.5, wherein an amount of the isocyanic acid compound is not less than 0.9 times by mole and not more than 1.1 times by mole relative to an amount of the tert-leucine. According to the present invention, it becomes possible to easily produce an N-carbamoyl-tert-leucine with high efficiency, while the generation of by-products such as a dipeptide-like compound and a urea compound is prevented.

Inventors:
川嵜 宏明
前原 克治
諸島 忠
Application Number:
JP2009541113A
Publication Date:
January 07, 2015
Filing Date:
November 07, 2008
Export Citation:
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Assignee:
株式会社カネカ
International Classes:
C07C273/18; C07B53/00; C07C275/16
Domestic Patent References:
JPS60155968A1985-08-16
JP2001049232A2001-02-20
JPH09235263A1997-09-09
JPS5414938A1979-02-03
JPH0386844A1991-04-11
Attorney, Agent or Firm:
Hisakazu Ueki
Hisahiko Ueki
Tadashi Sugawa
Hiroaki Ito