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Title:
環状化合物の製造方法
Document Type and Number:
Japanese Patent JP4349913
Kind Code:
B2
Abstract:
The present invention provides a method for preparing a beta -lactam compound of the following Formula (3), which comprises the step of reacting a compound of the following Formula (1) with a trialkyl phosphite represented by the formula (R<5>O)3P (wherein R<5> represents an ethyl group, etc.) in an amount of 2 to 5 moles per mole of the compound and the step of heating the resulting reaction mixture in a diluent, wherein said method is characterized by having the step of completely removing unreacted trialkyl phosphite from the reaction mixture prior to the step of heating. (wherein X represents S, etc., Y represents N, etc., n represents 0 or 1, R<1> represents an optionally substituted alkyl group containing 1 to 10 carbon atoms, etc., R<2> and R<3> each represent an optionally substituted alkyl or heterocyclic group, etc., and R<4> represents an alkenyloxy group containing 1 to 6 carbon atoms, etc., provided that R<1> and R<2> may together form a beta -lactam ring, etc.)

Inventors:
Akira Kaneko
Application Number:
JP2003578304A
Publication Date:
October 21, 2009
Filing Date:
March 26, 2003
Export Citation:
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Assignee:
Nippon Soda Co., Ltd.
International Classes:
C07F7/18; C07D403/12; C07D499/00; C07D499/04; C07D501/00; C07D501/02; C07D503/02; C07D505/02; C07D499/88; C07D499/897
Domestic Patent References:
JP62045589A
JP6345773A
Foreign References:
WO1993003042A1
Attorney, Agent or Firm:
Kazuo Shamoto
Yasushi Kobayashi
Akio Chiba
Hiroyuki Tomita
Takumi Terachi
Tadashi Masui