Title:
METHOD FOR PRODUCING HYDRAZONE COMPOUNDS
Document Type and Number:
Japanese Patent JP2009292726
Kind Code:
A
Abstract:
To provide a method for commercially advantageously producing a hydrazone compound useful as an intermediate for producing medicines.
L-rhamnose diethylmercaptal is reacted with hydrogen peroxide in the presence of tungstic acid and phospho-oxo acid to obtain a dialkylsulfonylmethane derivative. The derivative is reacted with a hydrazine compound to produce the hydrazone derivative of formula (4) wherein, R3 is H or OH; R4, R5 are each H, an alkyl group or an aryl group.
Inventors:
TAZAWA SHINNOSUKE
KIYONO HIROMI
MIYAGAKI MITSUHIRO
YOSHINO HIROSHI
KIYONO HIROMI
MIYAGAKI MITSUHIRO
YOSHINO HIROSHI
Application Number:
JP2006249156A
Publication Date:
December 17, 2009
Filing Date:
September 14, 2006
Export Citation:
Assignee:
SHIRATORI PHARM
ASUBIO PHARMA CO LTD
ASUBIO PHARMA CO LTD
International Classes:
C07C249/16; C07C251/76; C07C315/04; C07C317/18; C07B61/00
Attorney, Agent or Firm:
Alga Patent Office, a patent business corporation
Miyuki Ariga
Toshio Takano
Toshio Nakajima
Masaki Murata
Hiroto Yamamoto
Hiromi Matoba
Moriya Kataka
Ohno Shiki
Masahiro Matsuda
Nobuhiro Nonaka
Miyuki Ariga
Toshio Takano
Toshio Nakajima
Masaki Murata
Hiroto Yamamoto
Hiromi Matoba
Moriya Kataka
Ohno Shiki
Masahiro Matsuda
Nobuhiro Nonaka