Title:
ヒドロキシアルキルデンプン誘導体の製造方法
Document Type and Number:
Japanese Patent JP4688494
Kind Code:
B2
Abstract:
The present invention relates to hydroxyalkylstarch (HAS)-polypeptide-conjugate (HAS-polypeptide) comprising one or more HAS moecules, wherein each HAS is conjugated to the polypeptide via a carbohydrate moiety or a thioether as well as to methods for the production thereof. In a preferred embodiment, the polypeptide is erythropoietin (EPO).
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Inventors:
Zander, Norbert
Konrad, Halalto
Eichner, Wolfram
Konrad, Halalto
Eichner, Wolfram
Application Number:
JP2004535070A
Publication Date:
May 25, 2011
Filing Date:
August 08, 2003
Export Citation:
Assignee:
Fresenius Mold, Deutschland Gesellschaft Mitt Beschlenktel Haftung
International Classes:
C08B31/12; A61K8/73; A61K9/00; A61K9/14; A61K38/18; A61K38/22; A61K47/48; A61P7/00; A61P7/06; A61P43/00; C07K14/505; C07K14/53; C07K14/54; C07K14/55; C07K14/56; C07K14/565; C07K17/06; C07K17/10; C08B31/00; C08B31/08; C08B33/04; C08B35/04; C12N15/12; A61K38/00
Domestic Patent References:
| JPS56500495A | 1981-04-16 | |||
| JP2004525170A | 2004-08-19 | |||
| JP2000514434A | 2000-10-31 | |||
| JPH07196925A | 1995-08-01 | |||
| JP2006511635A | 2006-04-06 | |||
| JP2006516534A | 2006-07-06 |
Foreign References:
| DE3029307A1 | 1982-03-04 |
Attorney, Agent or Firm:
Shoichi Okuyama
Arihara Koichi
Matsushima Tetsuo
Hidefumi Kawamura
Naomi Yoshida
Ayako Nakamura
Fukagawa Eri
Satoshi Morimoto
Kyoko Tsunoda
Arihara Koichi
Matsushima Tetsuo
Hidefumi Kawamura
Naomi Yoshida
Ayako Nakamura
Fukagawa Eri
Satoshi Morimoto
Kyoko Tsunoda