Title:
イソニコチン酸誘導体の製造方法
Document Type and Number:
Japanese Patent JP4633123
Kind Code:
B2
Abstract:
The present invention relates to a process for the manufacture of compounds of formula Ia or Ib and pharmaceutically acceptable additional salts thereof, wherein R is lower alkyl. The compounds of formula Ia or Ib are valuable intermediate products for the manufacture of compounds that are pharmaceutically active as adenosine A2a receptor antagonist or metabotropic Glutamate receptor 2 antagonist. Such compounds are important in the regulation of many aspects of cellular metabolism and in the modulation of different central nervous system activities.
Inventors:
Spur, Paul
Application Number:
JP2007539508A
Publication Date:
February 16, 2011
Filing Date:
October 27, 2005
Export Citation:
Assignee:
F. HOFFMANN-LA ROCHE AKTIENGESELLSCHAFT
International Classes:
C07D213/79
Other References:
J.A.RAGAN,SYNTHESIS,2002年,N4,P483-486
Attorney, Agent or Firm:
Hajime Tsukuni
Koshiro Tsukuda
Fusayuki Saito
Koshiro Tsukuda
Fusayuki Saito