To provide a method for producing a liquid crystal compound by esterification reaction of a center part precursor having a phenolic hydroxy group and a side chain part precursor having a carboxy group, in which organic salts are removed efficiently after the esterification reaction, and a target liquid crystal compound is isolated efficiently in high purity.
The method for producing liquid crystal compound includes: a step (I) for carrying out reaction of the center part precursor which has a phenolic hydroxy group and which can be the center part of the liquid crystal compound and a mixed acid anhydride of the side chain precursor which has a carboxy group and which can be side chain parts of the liquid crystal compound, in an inert solvent to obtain a reaction liquid containing a liquid crystal compound in which the phenolic hydroxy group of the center part precursor and the carboxy group of the side chain part precursor are ester-bonded; a step (II) for adding a first alcohol in a prescribed amount to the reaction liquid obtained in the step (I), stirring the whole liquid, and adding water and optionally an organic solvent immiscible with water thereby carrying out liquid separation; and a step (III) for adding a second alcohol in a prescribed amount to the reaction liquid obtained in the step (II) thereby crystallizing the liquid crystal compound.
JP2010030974A | 2010-02-12 | |||
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JP2010030974A | 2010-02-12 |
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