Title:
METHOD FOR PRODUCING NANOPARTICLE BY FLUIDIZED BED SPRAY DRYING
Document Type and Number:
Japanese Patent JP2010090132
Kind Code:
A
Abstract:
To provide a method for producing nanoparticles of a poorly water-soluble or substantially water-insoluble compound applicable for pharmaceuticals, foods, and cosmetics.
The nanometer-size particles of a poorly water-soluble or substantially water-insoluble compound are produced by finely spraying a solution of the compound as a non-aqueous solvent or a mixture of an aqueous solvent and a non-aqueous solvent into a heated and fluidized bed of carrier excipient. The resulting product consists of a free flowing mixture of relatively large particles of the carrier excipient and the nanometer-size particles (not greater than 3 m) of the compound.
Inventors:
KERKHOF NICHOLAS J
Application Number:
JP2009270841A
Publication Date:
April 22, 2010
Filing Date:
November 27, 2009
Export Citation:
Assignee:
KERKHOF NICHOLAS J
International Classes:
A23L1/00; A23L1/30; A61K9/16; A61J3/02; A61K8/02; A61K8/34; A61K8/60; A61K9/51; A61K31/175; A61K31/56; A61K31/57; A61K31/70; A61K45/00; A61K47/10; A61K47/12; A61K47/18; A61K47/20; A61K47/22; A61K47/26; A61K47/28; A61K47/32; A61K47/36; A61K47/38; A61K47/42; A61P25/00; A61P25/08; C07J7/00
Domestic Patent References:
| JPH115746A | 1999-01-12 | |||
| JP2003518038A | 2003-06-03 | |||
| JPH0578251A | 1993-03-30 | |||
| JPH0820537A | 1996-01-23 |
Attorney, Agent or Firm:
Sonoda Yoshitaka
Kobayashi Yoshinori
Kobayashi Yoshinori