METHOD FOR PRODUCING OPTICALLY ACTIVE 4-OXY-2-ARYL-2-ALKYLSILOXYBUTYRONITRILE

Title:

METHOD FOR PRODUCING OPTICALLY ACTIVE 4-OXY-2-ARYL-2-ALKYLSILOXYBUTYRONITRILE

Document Type and Number:

Japanese Patent JP2004123624

Kind Code:

A

Abstract:

To provide a method for catalytically synthesizing an optically active 4-oxy-2-aryl-2-alkylsiloxybutyronitrile without using any highly toxic osmium compound.

The method for producing the optically active 4-oxy-2-aryl-2-alkylsiloxybutyronitrile comprises carrying out a reaction of a compound of formula(I)( wherein, Ar is an aryl or heteroaryl; and R1 is H or a hydroxyl-protective group ) with a cyanating agent in the presence of an optically active catalyst.

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Inventors:

TAKAMURA MINORU
YABU KAZUO
YANAGISAWA HIROAKI

Application Number:

JP2002290889A

Publication Date:

April 22, 2004

Filing Date:

October 03, 2002

Export Citation:

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Assignee:

SANKYO CO

International Classes:

C07B53/00; C07B61/00; C07F7/18; (IPC1-7): C07F7/18

Attorney, Agent or Firm:

Akio Ohno
Nakata Yasu Male
Toshiaki Yaguchi
Reiko Kanehara

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