Title:
光学活性を有するアルコール及びカルボン酸の製造方法
Document Type and Number:
Japanese Patent JP4763462
Kind Code:
B2
Abstract:
The present invention provides a method for producing (R)- or (S)-3-methyl carboxylic acid represented by the following formula (5):
wherein R 1 represents an alkyl group containing 3 to 5 carbon atoms, and * represents an asymmetric carbon,
which comprises decarboxylating (R)- or (S)-1-methylalkyl malonic acid having optical activity represented by the following formula (1) in the presence of a highly polar solvent and/or an additive for promoting decarboxylation:
wherein R 1 has the same definition as described above, and * represents an asymmetric carbon.
Inventors:
Yasukata Dekishima
Jun Kawabata
Hirotoshi Hiraoka
Makoto Ueda
Hisatoshi Uehara
Jun Kawabata
Hirotoshi Hiraoka
Makoto Ueda
Hisatoshi Uehara
Application Number:
JP2005517830A
Publication Date:
August 31, 2011
Filing Date:
February 04, 2005
Export Citation:
Assignee:
AP Corporation Co., Ltd.
International Classes:
C12P7/04; C07B53/00; C07B61/00; C07C51/00; C07C51/09; C07C51/38; C07C53/126; C07C55/02; C07C55/08; C07C67/343; C07C303/28; C12N15/09; C12N15/53; C12P7/40; C12P7/44; C07C309/66
Other References:
Tetrahedron:Asymmetry,2002年,Vol.13,p.971-974
Biosci.Biotechnol.Biochem.,1999年,Vol.63,No.10,p.1721-1729
J.Am.Chem.Soc.,1950年,Vol.72,4695-4697
Chem.Commun.,2004年 2月24日,Vol.7,p.792-793
Khim.-Farm.Zh,1972年,7/2,37-8
Biosci.Biotechnol.Biochem.,1999年,Vol.63,No.10,p.1721-1729
J.Am.Chem.Soc.,1950年,Vol.72,4695-4697
Chem.Commun.,2004年 2月24日,Vol.7,p.792-793
Khim.-Farm.Zh,1972年,7/2,37-8
Attorney, Agent or Firm:
Patent Service Corporation Patent Office Sykes