Title:
METHOD FOR PRODUCING OPTICALLY ACTIVE ALPHA- AMTNONITRILE AND ALPHA-AMINO ACIDS
Document Type and Number:
Japanese Patent JP3634207
Kind Code:
B2
Abstract:
PROBLEM TO BE SOLVED: To provide a new method for producing an optically active α- aminonitrile and optically active α-amino acids are obtained from the aminonitrile. The α-aminonitrile is obtained by asymmetric synthesis in high yield and with high stereoselectivity without synthesizing an imine even when starting material is unstable.
SOLUTION: This method for producing an optically active α-aminonitrile is comprises reacting an aldehyde compound and an amine compound with hydrogen cyanide in the presence of a chiral zirconium catalyst obtained by mixing a zirconium alkoxide with a binaphthol compound.
Inventors:
Osamu Kobayashi
Haruro Ishitani
Haruro Ishitani
Application Number:
JP26121099A
Publication Date:
March 30, 2005
Filing Date:
September 14, 1999
Export Citation:
Assignee:
Japan Science and Technology Agency
International Classes:
B01J31/18; B01J31/22; C07B53/00; C07B61/00; C07C227/18; C07C227/26; C07C229/08; C07C253/00; C07C253/08; C07C255/24; C07D211/60; C07C255/25; C07C255/31; C07C255/33; C07C255/42; (IPC1-7): C07C253/08; C07B53/00; C07C227/18; C07C229/08; C07C255/24; C07D211/60
Domestic Patent References:
| JP11253813A | ||||
| JP11255730A | ||||
| JP3240760A | ||||
| JP50059377A | ||||
| JP11033407A |
Attorney, Agent or Firm:
Toshio Nishizawa