Title:
光学活性含フッ素カルボニル-エン生成物の製造方法
Document Type and Number:
Japanese Patent JP5090773
Kind Code:
B2
Abstract:
An optically active, fluorine-containing carbonyl-ene product is produced by reacting a fluorine-containing ±-ketoester with an alkene in the presence of a transition metal complex having an optically active ligand. There are Mode 1 of conducting this reaction in the absence of reaction solvent, Mode 2 of conducting this reaction in a solvent that is low in relative dielectric constant, and Mode 3 of conducting this reaction in a halogenated hydrocarbon-series solvent. In each of these three modes, it is possible to produce the optically active, fluorine-containing carbonyl-ene product with low cost.
Inventors:
Koichi Mikami
Kosuke Aikawa
Akio Ishii
Kaori Mogi
Takafumi Otsuka
Kosuke Aikawa
Akio Ishii
Kaori Mogi
Takafumi Otsuka
Application Number:
JP2007108681A
Publication Date:
December 05, 2012
Filing Date:
April 17, 2007
Export Citation:
Assignee:
National University Corporation Tokyo Institute of Technology
Central Glass Co., Ltd.
Central Glass Co., Ltd.
International Classes:
C07C67/347; C07C69/732; C07B53/00; C07B61/00
Foreign References:
| US20060116396 | ||||
| US20060229305 |
Other References:
Tetrahedron:Asymmetry,2004年,Vol.15, Issue 24,p.3885-3889
Journal of Organic Chemistry,2006年12月22日,Vol.71, No.26,p.9751-9764
Journal of Organic Chemistry,2006年12月22日,Vol.71, No.26,p.9751-9764
Attorney, Agent or Firm:
Makoto Koide