Title:
ステロイド結晶の製造法、この方法によって得られた結晶および得られた結晶の医薬製剤における使用
Document Type and Number:
Japanese Patent JP4490116
Kind Code:
B2
Abstract:
The process for making steroid crystals having a predetermined average particle size of from 1 mum to 25 mum and a maximum particle size that does not exceed a predetermined maximum value of 100 mum, includes subjecting a supersaturated solution containing a steroid to a wet milling by wet milling apparatus while crystallizing, in order to obtain a primary particle suspension. Crystals obtained according to this process and pharmaceutical preparations containing them are also described.
Inventors:
Grab, De Treff
Gerek, hagen
Hazel, Peter
Aichart, Anette
Greasing, Sabine
Muller, Ube
Gerek, hagen
Hazel, Peter
Aichart, Anette
Greasing, Sabine
Muller, Ube
Application Number:
JP2003587830A
Publication Date:
June 23, 2010
Filing Date:
April 22, 2003
Export Citation:
Assignee:
SCHERING AKTIENGESELLSCHAFT
International Classes:
A61K31/56; C07J1/00; A61K9/14; A61K31/567; A61K31/568; A61P43/00; C07J41/00
Domestic Patent References:
| JP2005523333A | ||||
| JP5503305A | ||||
| JP3017014A | ||||
| JP4500925A |
Foreign References:
| WO2000039076A1 |
Other References:
STECKEL H,INTERNATIONAL JOURNAL OF PHARMACEUTICS,NL,1997年,V152 N1,P99-110
Attorney, Agent or Firm:
Hironobu Onda
Makoto Onda
Makoto Onda