Title:
チアゾール誘導体の製造法
Document Type and Number:
Japanese Patent JP4759388
Kind Code:
B2
Abstract:
A process for producing a compound of formula (5) or a salt thereof:
[F10]
wherein the process is characterized by comprising reacting a compound of formula (2) or a salt thereof:
[F8]
with an alkali metal nitrite in the presence of a reducing agent in an aqueous solution of an acidic compound, to thereby obtain a compound of formula (6) or a salt thereof:
[F9]
and reacting the obtained compound or a salt thereof with trihalogenoacetyl halide in the presence of a base, followed by hydrolysis.
Inventors:
Nagasawa Daishi
Koji Sato
Tsutomu Yagi
Yasuo Kitani
Koji Sato
Tsutomu Yagi
Yasuo Kitani
Application Number:
JP2005515462A
Publication Date:
August 31, 2011
Filing Date:
November 12, 2004
Export Citation:
Assignee:
Daiichi Sankyo Co., Ltd.
International Classes:
C07D513/04; A61K31/444; A61P7/02; A61P43/00; C07B39/00; C07B41/08; C07B43/04; C07B43/06
Domestic Patent References:
| JP4630267B2 | 2011-02-09 | |||
| JP4109288B2 | 2008-07-02 | |||
| JP4601053B2 | 2010-12-22 | |||
| JP2003104975A | 2003-04-09 | |||
| JP2001294572A | 2001-10-23 |
Attorney, Agent or Firm:
Alga Patent Office, a patent business corporation
Miyuki Ariga
Toshio Takano
Toshio Nakajima
Masaki Murata
Hiroto Yamamoto
Hiromi Matoba
Moriya Kataka
Ohno Shiki
Masahiro Matsuda
Nobuhiro Nonaka
Miyuki Ariga
Toshio Takano
Toshio Nakajima
Masaki Murata
Hiroto Yamamoto
Hiromi Matoba
Moriya Kataka
Ohno Shiki
Masahiro Matsuda
Nobuhiro Nonaka