Title:
METHOD FOR RACEMIZING OPTICALLY ACTIVE DIAMINE
Document Type and Number:
Japanese Patent JP3230300
Kind Code:
B2
Abstract:
PURPOSE: To safely carry out the racemization with good operating efficiency by performing thermal reaction of a specific optically active diamine in the presence of hydrogen together with a catalytic reduction catalyst in a simple pressure-resistant reactional vessel.
CONSTITUTION: An optically active diamine expressed by the formula (R1 is H, alkyl or allyl; R2 is alkyl or allyl; R1 and R2 are 2-6C alkyl bound to form a ring) is heated at about 90-170°C in the presence of hydrogen together with a catalytic reduction catalyst (Raney nickel or Raney cobalt is especially preferred) to carry out the racemization. The optically active diamine can be racemized at a high racemization ratio according to this method. Thereby, the optically active diamine can be converted into a useful optically active substance in good yield by repeating the optical resolution after the racemization.
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Inventors:
Sakie Nakai
Haruyo Sato
Haruyo Sato
Application Number:
JP29189192A
Publication Date:
November 19, 2001
Filing Date:
October 30, 1992
Export Citation:
Assignee:
Toray Industries, Inc.
International Classes:
B01J25/00; C07B55/00; C07B57/00; C07B61/00; C07C209/68; C07C211/11; C07C211/18; C07C211/27; (IPC1-7): C07C209/68; C07B55/00; C07B57/00; C07C211/11; C07C211/18; C07C211/27
Domestic Patent References:
| JP63185943A | ||||
| JP3512569B1 |