Title:
銅触媒による酸化剤としての酸素でアルコールを酸化してアルデヒド又はケトン類化合物を調製する方法及び応用
Document Type and Number:
Japanese Patent JP2022520528
Kind Code:
A
Abstract:
本発明は、銅触媒による酸化剤としての酸素でアルコールを酸化してアルデヒド又はケトン類化合物を調製する方法を開示する。室温で、銅塩、ニトロキシドラジカルを触媒とし、酸素又は空気を酸化剤とし、有機溶媒中で４～４８時間反応させ、アルコール類化合物を対応するアルデヒド又はケトン類化合物に効率的に酸化する。本発明の方法は、操作が簡単であり、設備に腐食性がある塩化物の使用を回避し、原料と試薬が入手しやすく、反応条件が穏やかで、基質適用性が広く、官能基の相溶性が良く、分離精製が容易であり、プロセス全体は環境にやさしく、汚染がなく、工業化生産に適した方法である。【選択図】なし
Inventors:
Akira Aso
Application Number:
JP2021543125A
Publication Date:
March 31, 2022
Filing Date:
January 17, 2020
Export Citation:
Assignee:
FUDAN UNIVERSITY
International Classes:
C07C45/39; C07C45/38; C07C47/02; C07C47/21; C07C47/24; C07C47/277; C07C47/55; C07C49/04; C07C49/207; C07C49/21; C07C49/217; C07C49/303; C07C49/788; C07C49/794; C07C49/807; C07C49/825; C07C49/84; C07C67/313; C07C69/76; C07C201/14; C07C205/45; C07C253/30; C07C255/56; C07D307/46; C07D333/22
Domestic Patent References:
| JP2014172874A | 2014-09-22 |
Foreign References:
| CN103420748A | 2013-12-04 | |||
| CN101544548A | 2009-09-30 |
Other References:
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HOOVER, J. M. AND STAHL, S. S.: "Highly Practical Copper(I)/TEMPO Catalyst System for Chemoselective Aerobic Oxidation of Primary Alc", J. AM. CHEM. SOC., vol. 133, JPN6022026276, 2011, pages 16901 - 16910, XP055811848, ISSN: 0004984046, DOI: 10.1021/ja206230h
CECCHETTO, A. ET AL.: "Efficient Mn-Cu and Mn-Co-TEMPO-catalysed oxidation of alcohols into aldehydes and ketones by oxygen", TETRAHEDRON LETTERS, vol. 42, JPN6022026278, 2001, pages 6651 - 6653, XP004301156, ISSN: 0004984047, DOI: 10.1016/S0040-4039(01)01245-X
ARENDS,I.W. ET AL.: "Modern oxidation of alcohols using environmentally benign oxidants", MODERN OXIDATION METHODS, vol. 2nd Edition, JPN6022026279, 2010, pages 147 - 185, ISSN: 0004813495
HOOVER, J. M. AND STAHL, S. S.: "Highly Practical Copper(I)/TEMPO Catalyst System for Chemoselective Aerobic Oxidation of Primary Alc", J. AM. CHEM. SOC., vol. 133, JPN6022026276, 2011, pages 16901 - 16910, XP055811848, ISSN: 0004984046, DOI: 10.1021/ja206230h
CECCHETTO, A. ET AL.: "Efficient Mn-Cu and Mn-Co-TEMPO-catalysed oxidation of alcohols into aldehydes and ketones by oxygen", TETRAHEDRON LETTERS, vol. 42, JPN6022026278, 2001, pages 6651 - 6653, XP004301156, ISSN: 0004984047, DOI: 10.1016/S0040-4039(01)01245-X
ARENDS,I.W. ET AL.: "Modern oxidation of alcohols using environmentally benign oxidants", MODERN OXIDATION METHODS, vol. 2nd Edition, JPN6022026279, 2010, pages 147 - 185, ISSN: 0004813495
Attorney, Agent or Firm:
Cosmos International Patent and Trademark Office
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